Peter S Nelson Selected Research

Androgens

1/2022	Therapeutic Implications for Intrinsic Phenotype Classification of Metastatic Castration-Resistant Prostate Cancer.
12/2021	Reciprocal YAP1 loss and INSM1 expression in neuroendocrine prostate cancer.
11/2021	Circulating and Intratumoral Adrenal Androgens Correlate with Response to Abiraterone in Men with Castration-Resistant Prostate Cancer.
1/2021	Cabozantinib can block growth of neuroendocrine prostate cancer patient-derived xenografts by disrupting tumor vasculature.
1/2021	The heterogeneity of prostate cancers lacking AR activity will require diverse treatment approaches.
1/2021	Reprogramming of the FOXA1 cistrome in treatment-emergent neuroendocrine prostate cancer.
1/2021	Targeting backdoor androgen synthesis through AKR1C3 inhibition: A presurgical hormonal ablative neoadjuvant trial in high-risk localized prostate cancer.
1/2020	Durable Response of Enzalutamide-resistant Prostate Cancer to Supraphysiological Testosterone Is Associated with a Multifaceted Growth Suppression and Impaired DNA Damage Response Transcriptomic Program in Patient-derived Xenografts.
12/2019	Association of prostate cancer SLCO gene expression with Gleason grade and alterations following androgen deprivation therapy.
10/2019	Molecular determinants of response to high-dose androgen therapy in prostate cancer.

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Peter S Nelson Research Topics

Disease

217	Prostatic Neoplasms (Prostate Cancer) 01/2022 - 01/2002
169	Neoplasms (Cancer) 01/2022 - 02/2002
37	Neoplasm Metastasis (Metastasis) 01/2022 - 01/2006
21	Carcinoma (Carcinomatosis) 01/2022 - 07/2002
9	Disease Progression 01/2022 - 04/2008
8	Adenocarcinoma 01/2022 - 09/2002
7	Residual Neoplasm 01/2018 - 04/2008
5	Inflammation (Inflammations) 01/2016 - 09/2010
4	Breast Neoplasms (Breast Cancer) 11/2019 - 04/2011
4	Carcinogenesis 06/2006 - 09/2003
3	Infections 01/2020 - 05/2014
2	Hypoxia (Hypoxemia) 01/2021 - 01/2013
2	DNA Repair-Deficiency Disorders (Chromosome Instability Syndromes) 01/2019 - 01/2018
2	Microsatellite Instability 10/2018 - 01/2018
2	Circulating Neoplastic Cells 01/2018 - 01/2016
2	Retinoblastoma (Glioblastoma, Retinal) 04/2016 - 12/2010
2	Human Influenza (Influenza) 05/2014 - 01/2012
2	Prostatic Hyperplasia (Benign Prostatic Hyperplasia) 06/2011 - 03/2008
2	Prostatic Intraepithelial Neoplasia 02/2008 - 01/2006

Drug/Important Bio-Agent (IBA)

78	AndrogensIBA 01/2022 - 01/2002
77	Androgen Receptors (Androgen Receptor)IBA 01/2022 - 08/2002
50	Proteins (Proteins, Gene)FDA Link 01/2022 - 08/2002
31	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2006
15	abirateroneIBA 12/2021 - 09/2011
14	enzalutamideIBA 12/2021 - 07/2012
14	Prostate-Specific Antigen (Semenogelase)IBA 01/2020 - 08/2002
12	Testosterone (Sustanon)FDA Link 01/2020 - 11/2006
11	RNA (Ribonucleic Acid)IBA 01/2022 - 07/2005
11	Docetaxel (Taxotere)FDA Link 01/2022 - 10/2005
11	Messenger RNA (mRNA)IBA 01/2022 - 08/2002
11	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 12/2008
10	Phenobarbital (Luminal)FDA Link 01/2022 - 02/2002
9	Transcription Factors (Transcription Factor)IBA 01/2022 - 05/2012
9	EnzymesIBA 01/2021 - 06/2008
9	SteroidsIBA 01/2020 - 05/2006
8	Pharmaceutical PreparationsIBA 01/2022 - 08/2008
7	LigandsIBA 01/2019 - 08/2010
7	Complementary DNA (cDNA)IBA 08/2010 - 07/2002
6	Biological ProductsIBA 01/2022 - 09/2003
6	Abiraterone AcetateIBA 11/2021 - 11/2014
5	AntibodiesIBA 12/2020 - 03/2004
5	Leuprolide (Lupron)FDA LinkGeneric 01/2018 - 06/2010
4	PlatinumIBA 12/2021 - 01/2016
4	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 10/2021 - 10/2007
4	Phosphotransferases (Kinase)IBA 10/2021 - 04/2009
4	Dutasteride (Avodart)FDA Link 05/2017 - 02/2010
4	Hormones (Hormone)IBA 07/2016 - 01/2003
4	Peptide Hydrolases (Proteases)FDA Link 11/2014 - 01/2012
4	Estrogens (Estrogen)FDA Link 05/2010 - 07/2002
4	Dihydrotestosterone (Androstanolone)IBA 05/2010 - 04/2009
3	Poly(ADP-ribose) Polymerase InhibitorsIBA 12/2021 - 01/2020
3	Circulating Tumor DNAIBA 06/2021 - 01/2018
3	Cell-Free Nucleic AcidsIBA 06/2021 - 01/2019
3	NucleotidesIBA 01/2021 - 01/2009
3	Peptides (Polypeptides)IBA 12/2020 - 04/2011
3	Prednisone (Sone)FDA LinkGeneric 01/2018 - 09/2007
3	Gonadotropin-Releasing Hormone (GnRH)FDA Link 08/2017 - 11/2013
3	MicroRNAs (MicroRNA)IBA 01/2016 - 07/2008
3	Mitoxantrone (Novantrone)FDA LinkGeneric 02/2015 - 10/2007
3	Monoamine Oxidase (MAO)IBA 01/2014 - 07/2006
3	Insulin-Like PeptidesIBA 05/2013 - 11/2004
3	herbal preparation PC-SPESIBA 05/2005 - 07/2002
2	AntigensIBA 01/2021 - 05/2012
2	ChromatinIBA 01/2021 - 01/2017
2	Androgen Antagonists (Antiandrogens)IBA 01/2020 - 01/2017
2	Immunoglobulin G (IgG)IBA 01/2020 - 01/2020
2	taxaneIBA 01/2020 - 10/2005
2	Protein Isoforms (Isoforms)IBA 11/2019 - 09/2003
2	IntegrinsIBA 01/2019 - 01/2015
2	CholesterolIBA 01/2019 - 04/2008
2	Niclosamide FDA Link 01/2018 - 01/2018
2	Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA 10/2017 - 02/2015
2	Kallikreins (Kallikrein)IBA 01/2017 - 06/2006
2	ParaffinIBA 12/2016 - 10/2016
2	Formaldehyde (Formol)FDA Link 12/2016 - 10/2016
2	E2F Transcription FactorsIBA 04/2016 - 12/2010
2	Mitochondrial DNA (mtDNA)IBA 04/2016 - 01/2009
2	Flutamide (Eulexin)FDA LinkGeneric 03/2015 - 06/2010
2	Oncogene Proteins (Oncogene Protein)IBA 01/2015 - 06/2013
2	CytokinesIBA 06/2014 - 10/2007
2	Monoclonal AntibodiesIBA 05/2013 - 12/2009
2	Tumor Biomarkers (Tumor Markers)IBA 01/2013 - 10/2010
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 10/2012 - 11/2006
2	InterleukinsIBA 08/2012 - 12/2008
2	Interleukin-8 (Interleukin 8)IBA 08/2012 - 12/2008
2	Glycoproteins (Glycoprotein)IBA 05/2012 - 10/2010
2	ProteomeIBA 08/2011 - 04/2011
2	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 09/2010 - 09/2003
2	Estradiol (Delestrogen)FDA LinkGeneric 05/2010 - 10/2006
2	TubulinIBA 09/2007 - 10/2005

Therapy/Procedure

90	Castration 01/2022 - 02/2006
82	Therapeutics 01/2022 - 08/2002
29	Prostatectomy (Retropubic Prostatectomy) 01/2022 - 07/2006
20	Drug Therapy (Chemotherapy) 01/2022 - 10/2005
6	Neoadjuvant Therapy 05/2017 - 10/2007
5	Precision Medicine 06/2021 - 05/2015
4	Aftercare (After-Treatment) 01/2021 - 12/2005
3	Lasers (Laser) 01/2022 - 05/2008
3	Chemoprevention 02/2010 - 05/2005
2	Immunotherapy 01/2018 - 06/2015